NCT06547931

Duffy-null Associated Neutrphil Count (DANC) Pediatric Patients

Retrospective Analysis of a Cohort of Duffy-null Associated Neutrophil Count (DANC) Pediatric Patients

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 150 (actual)
• Sponsor: Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico · Academic / Other
• Sex: All
• Age: 16 Years
• Healthy volunteers: —

Summary

There are currently no clinical and laboratory data that well characterize this neutropenia associated with the Duffy-null phenotype, particularly for pediatric subjects. In particular there are no data on the frequency of immune neutropenia in DANC neutropenic pediatric subjects. The goal of this study is to : * define the frequency of immune neutropenia within the cohort of DANC subjects under study * evaluate the frequency of different degrees of neutropenia (mild-moderate-severe); * evaluate the possible association between different degrees of neutropenia and the presence of infections.

Conditions

• Neutropenia Autoimmune

Interventions

Type	Name	Description
OTHER	Data collection and analysis	Retrospective collection of clinical and laboratory data relating to the definition of the nature of neutropenia

Timeline

• Start date: 2024-06-30
• Primary completion: 2025-09-30
• Completion: 2025-11-30
• First posted: 2024-08-09
• Last updated: 2026-03-27

Locations

1 site across 1 country: Italy