NCT06546488

Cognitive Assessment Tools for Huntington's Disease.

Cognitive Assessment Tools for Individuals With Huntington's Disease.

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 76 (estimated)
• Sponsor: Ohio State University · Academic / Other
• Sex: All
• Age: 30 Years – 65 Years
• Healthy volunteers: —

Summary

The purpose of the current proposal is to expand understanding of two currently available cognitive tools that are not typically used in Huntington Disease (HD) clinical trials that might be useful both for initial screening and for clinical trial application. One is the Coding Test and the other is the Self-Administered Gerocognitive Examination (SAGE). Both the Coding Test and the SAGE have been used for assessments of individuals with other neurodegenerative diseases, including Alzheimer's Disease, Parkinson's Disease and Lewy Body Disease, but data is lacking on their use in individuals with HD.

Detailed description

Subjects will be recruited from the OSU Wexner Medical Center Huntington Society of America Center of Excellence Clinic. Subjects will be scheduled for a one-time visit to complete the study. The entire visit will take approximately 1-1.5 hours. Vital signs (weight, blood pressure, temperature, respiratory rate and pulse) will be conducted. The subject's medical records will be reviewed to obtain their demographics, current medications, medical/surgical/ HD family history, and HD diagnosis details. If any adverse events occur during the research visit they will be documented. Participants will complete cognitive, functional and motor assessments.

Conditions

• Huntington Disease

Interventions

Type	Name	Description
BEHAVIORAL	Assessments	A standardized assessment battery will be administered. It will consist of cognitive, functional and motor assessments.

Timeline

• Start date: 2025-06-20
• Primary completion: 2027-12-01
• Completion: 2027-12-01
• First posted: 2024-08-09
• Last updated: 2026-03-02

Locations

1 site across 1 country: United States