Trials / Not Yet Recruiting
Not Yet RecruitingNCT06545253
A New Diagnostic Paradigm for Retinitis Pigmentosa Secondary to USH2A Pathogenic Variants
- Status
- Not Yet Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 60 (estimated)
- Sponsor
- IRCCS Ospedale San Raffaele · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
Aim of the study is to perform a non-invasive multimodal retinal imaging investigation in a cohort of patients affected by USH2A retinitis pigmentosa (USH2A-RP), in order to develop a new diagnostic paradigm to categorize clinically relevant subgroups. All the procedures will be performed according to normal clinical practice. In addition, a novel quantitative profiling of serum microRNAs will be carried out in order to analyze the clinical importance of microRNA biomarkers in the clinical setting of the disease.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | microRNAs analysis | Patients will undergo routinary ophthalmological examination, multimodal retinal imaging and blood sampling |
Timeline
- Start date
- 2024-08-01
- Primary completion
- 2025-02-01
- Completion
- 2027-02-01
- First posted
- 2024-08-09
- Last updated
- 2024-08-09
Source: ClinicalTrials.gov record NCT06545253. Inclusion in this directory is not an endorsement.