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Active Not RecruitingNCT06545136

Long Term Follow-up Study of Type-1 Gaucher Subjects Post FLT201 Dose (GALILEO-2)

A Multicenter, Long-term, Follow-up Study to Investigate the Safety and Durability of Response Following Dosing of an Adeno-associated Viral Vector (FLT201) in Subjects With Gaucher Disease (GALILEO-2)

Status
Active Not Recruiting
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
75 (estimated)
Sponsor
Spur Therapeutics · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This is a multicenter, long-term, follow-up trial of participants with Gaucher disease type 1 who received FLT201 treatment in a preceding clinical trial. Participants will be followed for 5 years post-treatment.

Conditions

Interventions

TypeNameDescription
GENETICFLT201FLT201 is a replication-incompetent single-stranded (ss) recombinant adeno-associated virus (AAV) vector. The vector is composed of a ss DNA genome packaged in an AAV-derived protein capsid.

Timeline

Start date
2024-05-13
Primary completion
2029-05-01
Completion
2029-05-01
First posted
2024-08-09
Last updated
2025-11-04

Locations

4 sites across 4 countries: United States, Brazil, Spain, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT06545136. Inclusion in this directory is not an endorsement.

Long Term Follow-up Study of Type-1 Gaucher Subjects Post FLT201 Dose (GALILEO-2) (NCT06545136) · Clinical Trials Directory