NCT06542172

Impact of Low-fat and Full-fat Milk on Lipids and Cardiac Function in Patients With Coronary Artery Disease

Impact of Low-fat and Full-fat Milk on Lipids and Cardiac Function in Patients With Coronary Artery Disease: A Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 120 (actual)
• Sponsor: Chinese PLA General Hospital · Academic / Other
• Sex: All
• Age: 30 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

This trial aimed to investigate the effects of low-fat and full-fat milk on patients with coronary artery disease (CAD).

Detailed description

The effects of low-fat and full-fat milk on lipid profiles and sphingolipid profiles in CAD patients are not well understood. In addition, milk intake is at a low level in the Chinese population compared with developed countries. Therefore, we aimed to conduct a randomized controlled trial to investigate the effects of low-fat and full-fat milk on lipid profiles, sphingolipid profiles, and cardiac performance in Chinese CAD patients.

Conditions

• Coronary Artery Disease

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	500 mL/day of full-fat milk from corn-fed cows (fat >3.8%) for 12 weeks	All milk is provided by the Inner Mongolia Yili Industrial Group Limited by Share Ltd (Inner Mongolia, China).
DIETARY_SUPPLEMENT	500 mL/day of full-fat milk from grass-fed cows (fat >3.8%) for 12 weeks	All milk is provided by the Inner Mongolia Yili Industrial Group Limited by Share Ltd (Inner Mongolia, China).
DIETARY_SUPPLEMENT	500 mL/day of low-fat milk (fat <1.5%) for 12 weeks	All milk is provided by the Inner Mongolia Yili Industrial Group Limited by Share Ltd (Inner Mongolia, China).

Timeline

• Start date: 2020-09-03
• Primary completion: 2021-03-04
• Completion: 2021-03-04
• First posted: 2024-08-07
• Last updated: 2024-08-07

Locations

7 sites across 1 country: China