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RecruitingNCT06541314

Fluzoparib Neoadjuvant Therapy for Ovarian Cancer

A Multicenter, Single-Arm Clinical Study of Fluzoparib Monotherapy As Neoadjuvant Treatment for Advanced Epithelial Ovarian Cancer

Status
Recruiting
Phase
Phase 2
Study type
Interventional
Enrollment
48 (estimated)
Sponsor
Qilu Hospital of Shandong University · Academic / Other
Sex
Female
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

This study is an interventional, single-arm, open-label clinical trial. To evaluate the safety and efficacy of Fluzoparib as neoadjuvant therapy in patients with FIGO stage III and IV , BRCA mutations or HRD positive epithelial ovarian cancer who cannot achieve R0 surgery as assessed by imaging (Suidan's CT score) or laparoscopy (Fagotti score), or cannot tolerate surgery.

Conditions

Interventions

TypeNameDescription
DRUGFluzoparibFluzoparib (50mg per capsule) 150mg po bid, with a treatment cycle of 28 days. Administer 2 cycles in total.

Timeline

Start date
2024-06-18
Primary completion
2026-05-31
Completion
2026-05-31
First posted
2024-08-07
Last updated
2024-11-27

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT06541314. Inclusion in this directory is not an endorsement.

Fluzoparib Neoadjuvant Therapy for Ovarian Cancer (NCT06541314) · Clinical Trials Directory