NCT06540209

Comparison of Effectiveness of Zinc Supplementation With ORS and Bacillus Clausii Versus Zinc With ORS and Saccharomyces Boulardii in Acute Watery Diarrhea in Paediatric Patients

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: RESnTEC, Institute of Research · Academic / Other
• Sex: All
• Age: 3 Months – 5 Years
• Healthy volunteers: Not accepted

Summary

The current study was carried out to directly compare the effectiveness of zinc supplementation with ORS and Bacillus clausii versus zinc with ORS and Saccharomyces boulardii among the local pediatric population presenting with acute watery diarrhea.

Detailed description

The results and importance of effective treatment for acute watery diarrhea in pediatric patients vary throughout the world. Previously, very limited literature was available comparing the efficacy of Bacillus clausii and Saccharomyces boulardii in acute watery diarrhea, providing mixed results. The current study aims to directly compare the effectiveness of zinc supplementation with ORS and Bacillus clausii versus zinc with ORS and Saccharomyces boulardii.

Conditions

• Acute Watery Diarrhea

Interventions

Type	Name	Description
DRUG	Bacillus clausii	Children will be give Bacillus clausii for 5 days
DRUG	Saccharomyces boulardii	Children will be give Saccharomyces boulardii for 5 days
DRUG	Zinc	Zinc will be given to all children for 5 days
DRUG	ORS	ORS will be given to all children for 5 days

Timeline

• Start date: 2023-04-01
• Primary completion: 2023-09-30
• Completion: 2023-09-30
• First posted: 2024-08-06
• Last updated: 2024-08-12

Locations

1 site across 1 country: Pakistan