NCT06539663

The Role of OmniLenz® in the Treatment of Small Corneal Perforations Secondary to Exposure Keratitis in ICU Patients

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 5 (actual)
• Sponsor: Farwaniya Hospital · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Case series of 5 ICU patients in Farwaniya Hospital who developed exposure keratitis and a subsequent small corneal perforation between April 2022 and April 2024. The investigators highlight the non-surgical role of OmniLenz® in the treatment of small corneal perforations secondary to exposure keratitis. The inclusion criteria were corneal perforation less than 1mm in size, positive culture \& sensitivity results and showing initial improvement on topical antibiotic eye drops.

Detailed description

The primary outcome measures were healing of the corneal perforation, a negative Seidel test and reformation of the anterior chamber. Secondary outcome measures were improvement of all three of ciliary injection, state of epithelial defect, and corneal infiltration.

Conditions

• Corneal Perforation
• Exposure Keratitis
• Infectious Keratitis

Interventions

Type	Name	Description
COMBINATION_PRODUCT	OmniLenz®	OmniLenz® applied for 1 week in all patients after development of corneal perforation

Timeline

• Start date: 2022-04-10
• Primary completion: 2024-02-10
• Completion: 2024-04-10
• First posted: 2024-08-06
• Last updated: 2024-08-06

Locations

1 site across 1 country: Kuwait