NCT06532825

Cardiac Autonomic Dysfunction As a Sign of Irreversible Advanced Heart Failure

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 200 (estimated)
• Sponsor: University Hospital Bispebjerg and Frederiksberg · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The main hypothesis is that autonomic dysfunction cannot improve among patients reaching end-stage heart failure. To evaluate this, patients admitted with acute decompensated heart failure in Bispebjerg hospital, and history one or more admissions with the same condition within the prior year, will undergo repeated brief heart monitoring (10 min). Baseline recordings (at admission) will be compared with equivalent measurements before discharge to explore whether heart rate variability increases. Patients will be followed for six months after discharge from the hospital.

Detailed description

If the patient accepts to participate and signed the project informed consent, their clinical record will be followed until the last patient included has been followed for six months.

Conditions

• Heart Failure

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	heart monitoring	individual comparison of heart rate variability at admission with a repeated measurement before discharge

Timeline

• Start date: 2024-08-01
• Primary completion: 2025-06-30
• Completion: 2025-12-31
• First posted: 2024-08-01
• Last updated: 2025-02-25

Locations

1 site across 1 country: Denmark