NCT06531356

Efficiency of Autologous Amniotic Fluid Injection in the Healing of Cesarean Section Scar in High-Risk Population

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 108 (actual)
• Sponsor: Kasr El Aini Hospital · Academic / Other
• Sex: Female
• Age: 30 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

The goal of this randomized controlled trial is to investigate the effect of injection of autologous amniotic fluid in the healing of the scar of cesarean section among high-risk population. Investigator's aim is to know : quality of wound healing, rate of infection and time needed for complete healing. Participants will be divided into two groups. All participants will undergo cesarean section. We will inject autologous amniotic fluid in the edges of the wound during skin closure in half of the participants. Wound healing will be assessed at 1st, 2nd and 6th week postoperatively.

Detailed description

After surgery, participants will be observed along 6 weeks (at 1, 2 and 6 weeks intervals) and scars will be assessed regarding color, thickness, pliability and presence of exudate.

Conditions

• High Risk Pregnancy
• Healing Surgical Wounds

Interventions

Type	Name	Description
BIOLOGICAL	autologous amniotic fluid	10 cc of amniotic fluid aspirated after opening uterine incision in cesarean section, then Injected in edges of skin before closure
OTHER	No amniotic fluid injected in skin edges	conventional closure of skin

Timeline

• Start date: 2024-02-16
• Primary completion: 2024-05-16
• Completion: 2024-05-20
• First posted: 2024-08-01
• Last updated: 2024-08-01

Locations

1 site across 1 country: Egypt