NCT06529757

Skin Wetting in Burn Survivors

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: University of Texas Southwestern Medical Center · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

This project will identify the efficacy of whole body skin wetting aimed to attenuate excessive elevations in internal body temperatures during physical activity in well-healed burn survivors. The investigators will conduct a randomized crossover design study. Non-burned control subjects, subjects who experienced burns covering \~20% to 40% of their body surface area, and subject having burns \>40% of their body surface area will be investigated. Subjects will exercise in heated environmental conditions while receiving no cooling or whole body skin wetting.

Conditions

• Burn Injury

Interventions

Type	Name	Description
OTHER	Whole body cooling	Subjects will exercise for 60 minutes in the indicated environmental condition while being exposed to whole body skin wetting. Skin wetting will be performed by spraying water onto the whole body throughout the exercise bout.
OTHER	Non-cooling	Subjects will exercise for 60 minutes in the indicated environmental condition while being exposed to no cooling modalities.

Timeline

• Start date: 2024-07-31
• Primary completion: 2026-07-31
• Completion: 2026-07-31
• First posted: 2024-07-31
• Last updated: 2025-10-21

Locations

1 site across 1 country: United States