NCT06528171

Covid-19 Long Immunité IMagerie (CLIIM)

Specific Markers of Covid-long Syndrome: Identifying the Mechanisms Involved With a View to Defining Diagnostic Criteria

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: Centre Hospitalier Universitaire de Nice · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Covid-long pathology affects a large number of patients, and represents a major medical, economic and societal challenge. To date, we have no objective criterion for a definitive diagnosis, nor any predictive tool for monitoring the evolution of Covid-long. Based on recruitment from the infectious diseases department of Nice University Hospital, the investigator's team wants to conduct an innovative pathophysiological study to better define the disease and identify specific biomarkers that could subsequently be used as a diagnostic tool for Covid-long. 120 participants will be initially included for the model learning phase: 60 controls in the CL- cohort and 60 patients in the CL+ cohort. Then 80 patients (40 CL+ and 40 Cl-) will be enrolled for the model validation phase.

Conditions

• COVID Long-Haul

Interventions

Type	Name	Description
PROCEDURE	Brain MRI	non injected brain MRI
BIOLOGICAL	Specific blood samples	blood samples to find immunological and inflammatory markers

Timeline

• Start date: 2024-12-06
• Primary completion: 2025-12-01
• Completion: 2026-09-01
• First posted: 2024-07-30
• Last updated: 2025-05-14

Locations

1 site across 1 country: France