NCT06528054

TreatmENT of AnastomotiC LeakagE After COLON Cancer Resection

TreatmENT of AnastomotiC LeakagE After COLON Cancer Resection: the TENTACLE - Colon Study

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 2,000 (estimated)
• Sponsor: Radboud University Medical Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This international multicentre retrospective cohort study aims to research anastomotic leakage after colon cancer resection and has two main objectives: 1. To identify predictive factors associated with 90-day mortality and 90-day Clavien-Dindo grade 4-5 complications amongst patients who developed AL following colon cancer resection and to develop and validate a prediction model for predicting 90-day mortality as well as the co-primary composite endpoint Clavien-Dindo grade 4-5 complications. 2. To explore and compare the effectiveness of various treatment strategies for AL following colon cancer resection, considering patient, tumour, resection and leakage characteristics.

Conditions

• Treatment
• Anastomotic Leakage
• Resection
• Colon Cancer

Interventions

Type	Name	Description
OTHER	Development of a model for predicting 90-day mortality and to compare various treatment strategies for anastomotic leakage	The prediction model and comparison of various treatment strategies will be studies when the data is available for analysis.

Timeline

• Start date: 2024-10-01
• Primary completion: 2025-03-01
• Completion: 2026-03-01
• First posted: 2024-07-30
• Last updated: 2024-07-30