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RecruitingNCT06527495

Clinical Pharmacogenetic Study of Sorafenib in Egyptian Patients With Hepatocellular Carcinoma

Clinical Pharmacogenetic Study of the Efficacy and Safety of Sorafenib in Egyptian Patients With Hepatocellular Carcinoma

Status
Recruiting
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
150 (estimated)
Sponsor
Assiut University · Academic / Other
Sex
All
Age
18 Years – 80 Years
Healthy volunteers
Not accepted

Summary

The current study will aim to maximize the therapeutic effect and to minimize the adverse effects of sorafenib in HCC through pharmacogenomic analysis of VEGFA and KDR genetic polymorphisms.

Conditions

Interventions

TypeNameDescription
DRUGSorafenibSorafenib Tablets (200 -400 mg) twice daily

Timeline

Start date
2023-01-01
Primary completion
2024-12-01
Completion
2024-12-01
First posted
2024-07-30
Last updated
2024-07-30

Locations

1 site across 1 country: Egypt

Source: ClinicalTrials.gov record NCT06527495. Inclusion in this directory is not an endorsement.

Clinical Pharmacogenetic Study of Sorafenib in Egyptian Patients With Hepatocellular Carcinoma (NCT06527495) · Clinical Trials Directory