NCT06526481

Nasoseptal Double Flap Versus Rescue Flap in Endoscopic Transsphenoidal Pituitary Surgery

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 56 (actual)
• Sponsor: Mansoura University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

This paper investigates the outcomes of two surgical techniques-nasoseptal double flap and nasoseptal rescue flap-used in endoscopic transsphenoidal surgery for pituitary tumors. The nasoseptal flap technique has significantly reduced the incidence of postoperative Cerebrospinal Fluid (CSF) leaks but can cause nasal morbidity.

Detailed description

The study aims to compare nasal morbidity and function between the two techniques in patients undergoing this type of surgery. Each patient's nasal morbidity, olfaction, and postoperative complications will be assessed using various tools.

Conditions

• Pituitary Adenoma

Interventions

Type	Name	Description
PROCEDURE	Endoscopic Transsphenoidal pituitary surgery : Double Nasoseptal Flap Technique	Patients with with symptomatic pituitary macroadenoma and tumor size ≥ 2 cm will have transsphenoidal endoscopic excision of pituitary adenoma. -On one side full sized nasoseptal flap will be elevated and a smaller sized nasoseptal flap will be elevated on the other side.
PROCEDURE	Endoscopic Transsphenoidal pituitary surgery : Rescue Flap Technique	Patients with with symptomatic pituitary macroadenoma and tumor size ≥ 2 cm will have transsphenoidal endoscopic excision of pituitary adenoma. \- A horizontal incision will be performed in the nasal septum in a posterior to anterior direction starting from the sphenoid ostium to a point opposite anterior end of the middle turbinate ( approximately up to one half of septum).

Timeline

• Start date: 2022-12-12
• Primary completion: 2024-03-26
• Completion: 2024-07-01
• First posted: 2024-07-29
• Last updated: 2024-08-12

Locations

1 site across 1 country: Egypt