NCT06526130

Influence of Anaesthesia Type on Multiple Sclerosis Relapse

Multiple Sclerosis Comparison of Relapse Incidence After General and Neuraxial Anesthesia: a Retrospective Observational Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 56 (actual)
• Sponsor: Varazdin General Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

The influence of anesthesia on the course of multiple sclerosis is poorly investigated and the literature is limited. The aim of this study is to investigate multiple sclerosis relapse after different types of anesthesia.

Detailed description

The influence of anesthesia on the course of multiple sclerosis is poorly investigated and the literature is limited. A possible relapse after neuraxial anesthesia, it is believed to be associated with local anesthetic's toxicity and concentration. The aim of this study is to investigate multiple sclerosis relapse after different types of anesthesia.

Conditions

• Multiple Sclerosis

Interventions

Type	Name	Description
PROCEDURE	General anaesthesia	Intravenous or volatile general anesthesia was preformed with different type of airway management (endotracheal tube, laryngeal mask and bag mask ventilation)
PROCEDURE	Neuraxial anaesthesia	spinal or epidural injections of local anesthetic with or without opioid

Timeline

• Start date: 2012-01-01
• Primary completion: 2022-12-31
• Completion: 2024-05-16
• First posted: 2024-07-29
• Last updated: 2024-07-30