NCT06525584

Ketamine Infusion as a Method of Cerebral Protection in Children

Ketamine Infusion in the Postoperative Period as a Method of Cerebral Protection in Children During Surgical Correction of Congenital Heart Defects

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 196 (estimated)
• Sponsor: Kemerovo State Medical University · Academic / Other
• Sex: All
• Age: 1 Month – 5 Years
• Healthy volunteers: Not accepted

Summary

The study is devoted to the use of ketamine infusion in a subanesthetic dose in the postoperative period in children after surgical correction of congenital heart defects in children.

Detailed description

The study will examine the safety and effectiveness for neuroprotection of subanesthetic doses of ketamine in the postoperative period in children undergoing operations to correct septal congenital heart defects using cardiopulmonary bypass.

Conditions

• Brain Injuries

Interventions

Type	Name	Description
DRUG	Ketamine Hcl 50Mg/Ml Inj	ketamine infusion at a dose of 0.1 mg/kg/hour for 16 hours
DRUG	Ketamine Hcl 50Mg/Ml Inj	ketamine infusion at a dose of 0.3 mg/kg/hour for 16 hours
OTHER	Control	Without ketamine

Timeline

• Start date: 2023-11-05
• Primary completion: 2025-12-01
• Completion: 2025-12-01
• First posted: 2024-07-29
• Last updated: 2024-07-29

Locations

1 site across 1 country: Russia