NCT06523933

Distribution of Bacteria in OME After Radiotherapy For NPC.

Distribution of Bacteria in Otitis Media With Effusion After Radiotherapy For Nasopharyngeal Carcinoma.

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 234 (estimated)
• Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Academic / Other
• Sex: All
• Age: 15 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

To observe the prognostic difference of tympanocentesis in different kinds of otitis media effusion.

Detailed description

This study is a prospective, observational clinical study to observe the difference in prognosis of tympanocentesis in different kinds of otitis media effusion (OME), especially OME after radiotherapy for nasopharyngeal carcinoma (NPC). A total of 234 patients diagnosed with OME who are given the treatment of tympanocentesis only, including outpatient and inpatient patients, were included in the study. The middle ear effusion collected during the tympanocentesis is sent for bacterial culture. The positive rate of the effusion and the recurrence rate within 24 weeks will be compared in order to figure out whether bacterial infection is an important influencing factor for some kinds of OME in addition to eustachian tube dysfunction, which is acknowledged.

Conditions

• Otitis Media Effusion
• Nasopharyngeal Carcinoma

Timeline

• Start date: 2024-05-12
• Primary completion: 2024-11-12
• Completion: 2025-05-12
• First posted: 2024-07-26
• Last updated: 2024-07-26

Locations

1 site across 1 country: China