NCT06523868

Evaluation of Multi-Cancer Early Detection Testing in a High-Risk Military Population: The Sentinel Study

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 1,500 (estimated)
• Sponsor: Dana-Farber Cancer Institute · Academic / Other
• Sex: All
• Age: 45 Years
• Healthy volunteers: Accepted

Summary

The purpose of this research study is to evaluate the possible benefits of an investigational, but commercially available Galleri multi-cancer early detection (MCED) blood test which is designed to detect many types of cancer early in veterans who have served in the military in active duty. The name of the screening blood test being studied is: -GRAIL Galleri MCED test

Detailed description

This research study aims to assess the performance of the Galleri multi-cancer early detection (MCED) screening test in a military population and to compare the number and types of cancers diagnosed using MCED testing versus standard of care. This research study will give doctors and participants results of Galleri® blood tests which is designed to detect many types of cancer. The research study procedures including screening for eligibility, blood draws, questionnaires, and clinic visits. Participation in this research study is expected to last for up to 1 year. It is expected that about 1,500 people will take part in this research study. The Department of Defense (DoD) is funding this study.

Conditions

• Cancer Diagnosis

Interventions

Type	Name	Description
OTHER	GRAIL Galleri	A multi-cancer early detection (MCED) blood test.

Timeline

• Start date: 2025-03-31
• Primary completion: 2027-09-30
• Completion: 2028-09-30
• First posted: 2024-07-26
• Last updated: 2026-02-27

Locations

1 site across 1 country: United States