NCT06522880

Cytomegalovirus (CMV) Transmission and Immune Tracking (TransmIT) Study

Cytomegalovirus (CMV) Transmission and Immune Tracking (TransmIT) Study: An Observational Study to Evaluate CMV Transmission and Immune Correlates of Viral Shedding Among Young Children in Early Education and Care Settings

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: University of Massachusetts, Worcester · Academic / Other
• Sex: All
• Age: 1 Day – 36 Months
• Healthy volunteers: Not accepted

Summary

The goal of STAGE I of the CMV TransmIT Study is to determine the prevalence of CMV shedding in children up to and including 36 months of age in large group childcare centers and in staff who regularly work at the center. Participants will complete a health survey and provide one saliva sample for CMV PCR testing. In addition, infrastructure for the study will be developed (e.g. community engagement to build the network of centers, data pipelines, digital platform, sampling workflows) and participant sample collection at home will be piloted. These activities will inform the design of STAGE II.

Conditions

• Cytomegalovirus Infections

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	CMV PCR on saliva	Observational study to measure prevalence of CMV shedding by saliva PCR

Timeline

• Start date: 2023-08-10
• Primary completion: 2027-01-31
• Completion: 2027-12-31
• First posted: 2024-07-26
• Last updated: 2024-07-26

Locations

1 site across 1 country: United States