Trials / Completed
CompletedNCT06520267
Prevalence of Bacteriuria, Antibiotic Susceptibility, and Treatment Response in Symptomatic Benign Prostatic Hyperplasia
Prevalence of Bacteriuria, Antibiotic Susceptibility, and Treatment Response in Patients With Symptomatic Benign Prostatic Hyperplasia: a Prospective Observational Study
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 131 (actual)
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine. · Academic / Other
- Sex
- Male
- Age
- 40 Years
- Healthy volunteers
- Not accepted
Summary
The goal of this prospective observational study is to identify the common pathogens and antibiotic sensitivity pattern in urine samples of men with symptomatic BPH and to assess severity of LUTS in patients with symptomatic BPH using IPSS score before and after antibiotic therapy.
Detailed description
This was a hospital-based prospective observational study. All patients with symptomatic BPH attending the Urology Out-Patient Department (OPD) of the study site were enrolled. Informed and written consent was obtained from all participants. Demographic data were recorded, and detailed histories were taken regarding the duration and symptoms of BPH, including incomplete bladder emptying, frequency, intermittency, urgency, weak stream, straining, nocturia, and relevant past history. IPSS scoring was conducted. A thorough clinical examination, including general physical, systemic, and digital rectal examination, was performed. During the rectal examination, the prostate was checked for nodules, softness, induration, or tenderness. Urine culture and antibiotic sensitivity tests were conducted to assess the bacteriological profile.
Conditions
- Bacteriuria in Symptomatic Benign Prostate Hyperplasia
- Antibiotic Susceptibility in Symptomatic Benign Prostate Hyperplasia
- Treatment Response to Antibiotics in Symptomatic Benign Prostate Hyperplasia
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Antibiotic therapy | Urine culture and antibiotic sensitivity tests were conducted to assess the bacteriological profile. The patients were then prescribed antibiotics based on susceptibility testing for a duration of 1 week. |
Timeline
- Start date
- 2020-09-01
- Primary completion
- 2021-06-12
- Completion
- 2021-08-15
- First posted
- 2024-07-25
- Last updated
- 2024-07-25
Locations
1 site across 1 country: Nepal
Source: ClinicalTrials.gov record NCT06520267. Inclusion in this directory is not an endorsement.