Trials / Recruiting
RecruitingNCT06516237
Development of Novel Imaging and Molecular Biomarkers of Fibrosis in Patient With Ulcerative Colitis
Relationships Between Intestinal Ultrasound Parameters and Elastography Measurements With Histopathologic Findings in a Prospective Cohort of Patients With Ulcerative Colitis: Development of Novel Imaging and Molecular Biomarkers of Fibrosis
- Status
- Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 50 (estimated)
- Sponsor
- IRCCS San Raffaele · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Prospective multicenter interventional non-randomized cross-sectional study. Ultrasound operators will be blinded to clinical and endoscopic findings and the endoscopist will be blinded of the clinical and ultrasound findings. This study aims to develop novel imaging and molecular biomarkers of fibrosis, through the use of intestinal ultrasound and shear wave elastography, using histologic specimens obtained by endoscopic biopsies as reference standard.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | to determine molecular and epigenetic biomarkers | In addition, up to 8 biopsies will be performed, at clinical judgment, in distal colon to determine molecular and epigenetic biomarkers. |
Timeline
- Start date
- 2024-11-21
- Primary completion
- 2026-07-31
- Completion
- 2026-07-31
- First posted
- 2024-07-23
- Last updated
- 2026-01-15
Locations
1 site across 1 country: Italy
Source: ClinicalTrials.gov record NCT06516237. Inclusion in this directory is not an endorsement.