NCT06515938

Study on New Strategies for Hepatitis B Virus Immunization

Comparative Immunogenicity of Hepatitis B Vaccine With Different Immunization Schedule in Primary Immune Adults Aged 25-55 in China

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 1,169 (actual)
• Sponsor: Wu Jiang · Other Government
• Sex: All
• Age: 25 Years – 55 Years
• Healthy volunteers: Accepted

Summary

To investigate the immunogenicity of HB vaccine with different series among primary immune adults aged 25-55, to assess potential alternative approaches for HB immunization.

Detailed description

By comparing the immunization effect of hepatitis B vaccine with other different types of hepatitis B vaccines using seris procedure, information on the immunization effect of 60 micrograms of hepatitis B vaccine in adults was obtained, which will provide a scientific basis for the development of a rapid immunization procedure for adults with large doses of hepatitis B vaccine and for the improvement of the immunization strategy for hepatitis B in adults.

Conditions

• Vaccine Reaction

Interventions

Type	Name	Description
BIOLOGICAL	20μg Engerix-B hepatitis B vaccine
BIOLOGICAL	20μg Kangtai hepatitis B vaccine
BIOLOGICAL	60μg Kangtai hepatitis B vaccine
BIOLOGICAL	20μg CHO

Timeline

• Start date: 2013-01-01
• Primary completion: 2014-06-30
• Completion: 2015-12-31
• First posted: 2024-07-23
• Last updated: 2024-07-24

Locations

2 sites across 1 country: China