NCT06515717

Exogenous Ketones and Behavior

Exogenous Ketones and Behavior (ExoKet)

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 45 (estimated)
• Sponsor: German Institute of Human Nutrition · Academic / Other
• Sex: All
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

The study will examine the effect of exogenous ketone ester on behavior and metabolism using Virtual Reality and computerizes behavioral tasks.

Detailed description

This study investigates the effects of exogenous ketone ester on behavior, cognition, and metabolism over one week of consumption. Using a within-subjects, randomized, crossover design, participants will undergo two phases: one with the ketone ester supplement and one with a calorie- and taste-matched placebo. The study includes four lab visits: visits 1 and 3 mark the first day of each intervention, while visits 2 and 4 mark the last day. During each visit, participants will complete behavioral tasks, questionnaires, and blood tests. Additionally, participants will record their food intake via an app and collect stool samples throughout the intervention.

Conditions

• Behavior

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	ketone ester	oral supplement
DIETARY_SUPPLEMENT	dextrose (placebo)	oral supplement calorie and taste matched to ketone supplement

Timeline

• Start date: 2024-07-18
• Primary completion: 2025-06-23
• Completion: 2025-06-23
• First posted: 2024-07-23
• Last updated: 2024-07-29

Locations

1 site across 1 country: Germany