NCT06511076

A Study to Evaluate Zilucoplan Injected Subcutaneously Either by a Prefilled Syringe or an Auto-injector in Healthy Adult Participants

An Open-Label, Single Center, Randomized, 2-Way Crossover, Single-Dose, Bioequivalence Study of Zilucoplan Injected Subcutaneously Either by a Prefilled Syringe or an Auto-Injector in Healthy Adult Participants

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 14 (actual)
• Sponsor: UCB Biopharma SRL · Industry
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to assess the bioequivalence pharmacokinetics, safety, tolerability and device deficiencies of zilucoplan (ZLP) in healthy adult participants

Conditions

• Healthy Volunteers

Interventions

Type	Name	Description
DRUG	Zilucoplan	Participants will receive a single sc injection of zilucoplan in the pre-specified sequence.

Timeline

• Start date: 2024-08-05
• Primary completion: 2024-11-26
• Completion: 2024-11-26
• First posted: 2024-07-19
• Last updated: 2026-01-06
• Results posted: 2026-01-06

Locations

1 site across 1 country: Netherlands