NCT06508255

Time-restricted Eating and Cognition

Time-restricted Eating and Cognition (ChronoBEAT)

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 35 (estimated)
• Sponsor: German Institute of Human Nutrition · Academic / Other
• Sex: Female
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

This study aims to investigate how time-restricted eating (TRE), more specifically TRE at different times (early vs late in the day), influences brain activity, behavior, decision-making, food intake, physical activity, the gut microbiome and metabolic processes. The study intervention procedure is a replication of that described in Peters et al. (2021).

Detailed description

This study aims to investigate the effects of different time-restricted eating (TRE) interventions on decision-making, brain activity and related processes in an all female cohort over 8 weeks. The study will have a within-subjects, randomised, crossover design, involving two TRE interventions with a comparable feeding and fasting window of 8:16h respectively- early TRE (eating window: 08:00-16:00) and late TRE (eating window: 13:00-21:00). After completing a screening visit, participants will complete a two-week observational phase in which they record their habitual food intake, as well as sleep and physical activity assessment. After this observational phase, participants will be randomly assigned to one of two study arms (early TRE/late TRE or late TRE/early TRE). Here they will complete both TRE interventions for two weeks each, separated by a washout phase of two weeks. During these phases they will record their food intake and physical activity and sleep will be assessed. The participants will be invited for 4 laboratory study visits during this time, at the beginning and end of each TRE intervention.

Conditions

• Time Restricted Eating
• Intermittent Fasting

Interventions

Type	Name	Description
BEHAVIORAL	Early Time-Restricted Eating	Eat between 8:00 and 16:00 for 2 weeks
BEHAVIORAL	Late Time-Restricted Eating	Eat between 13:00 and 21:00 for 2 weeks

Timeline

• Start date: 2024-05-17
• Primary completion: 2025-03-01
• Completion: 2025-03-01
• First posted: 2024-07-18
• Last updated: 2024-07-18

Locations

1 site across 1 country: Germany