NCT06506565

Low-Dose Ketamine Infusion During Burn Wound Care

A Randomized, Placebo-Controlled, Double-Blind Evaluation of Low-Dose Ketamine Infusion During Burn Wound Care Procedures to Improve Pain Intensity and Reduce Opioid Consumption

• Status: Recruiting
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 140 (estimated)
• Sponsor: University of Tennessee · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The current standard of care (SOC) (i.e. fentanyl and midazolam) offers limited efficacy for preventing or relieving pain. Ketamine infusions may provide the benefits of analgesia, minimize adverse events, and reduce opioid use. The purpose of this study is to determine if adding a low dose ketamine infusion during wound care will safely provide pain relief for patients with burn injury.

Conditions

• Burn
• Pain
• Dissociation
• Opioid

Interventions

Type	Name	Description
DRUG	Ketamine	Infusion during wound care
DRUG	0.9% NaCl	Infusion during wound care

Timeline

• Start date: 2024-07-08
• Primary completion: 2025-12-01
• Completion: 2025-12-01
• First posted: 2024-07-17
• Last updated: 2024-12-13

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study