NCT06502067

Efficacy of Serratus Posterior Intercostal Plane Block for Analgesia and Inflammatory Marker in Breast Surgery

Efficacy of Serratus Posterior Superior Intercostal Plane Block (SPSIPB) on Perioperative Analgesia and Inflamatory Markers in Breast Surgery

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (estimated)
• Sponsor: Ain Shams University · Academic / Other
• Sex: Female
• Age: 21 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

To study the efficiacy of serratus posterior superior block in controlling perioperative breast cancer surgery pain and its effect on inflamatory markers.

Detailed description

Back ground The presence of pain during the initial course of treatment in women with early-stage breast cancer was associated with significantly higher levels of c-reactive protein(CRP) ,interleukin-7(IL-7)and interleukin-13(IL-13) There is evidence of effectiveness of regional block in controlling inflamatory markers Serratus posterior superior intercostal plane block (SPSIPB) is a novel Regional technique that provides analgesia in the hemithorax, shoulder, and back of the neck which proved its efficacy in controlling pain after Video assisted thoracoscopic surgery there are little epidemiological data on (SPSIPB)usage in masectomy and lumpectomy procedures and its effect on inflamatory markers Methodology: * Type of the Study: Randomized prospective comparative controlled double-blinded study * Study Setting: Ain Shams University Hospitals * Study Period: One year after approval of the protocol. * Place :Ain shams university hospitals * Study Population: Adult patients who will undergo breast cancer surgey.

Conditions

• Breastcancer
• Perioperative Pain
• Inflammation

Interventions

Type	Name	Description
DRUG	Analgesia mangement group A,B	1gm of paracetamol, 30mg of ketorolac and 1mg Granitryl will be given twenty minutes before the end of the operation .

Timeline

• Start date: 2024-07-25
• Primary completion: 2025-06-02
• Completion: 2025-07-01
• First posted: 2024-07-15
• Last updated: 2024-07-23