NCT06501898

Tributyrin: Time Course & Efficacy to Improve Health & Performance

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 4 (actual)
• Sponsor: Florida State University · Academic / Other
• Sex: All
• Age: 30 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine if tributyrin supplementation improves metabolite concentrations, overall health biomarkers, and performance in sedentary men and women. The study would further understand the potential usage of tributyrin as a health and performance increasing supplement through improving gut and immune health, sleep, and performance as well as reduce inflammation. Participants will supplement for tributyrin for 4 weeks and complete fecal metabolite measures, cardiovascular evaluation, sleep assessment, and exercise testing as well as provide blood samples.

Conditions

• Metabolite Concentration
• Gut Permeability
• Inflammation
• Sleep
• Performance

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	CoreBiome	300 mg, once daily of tributyrin for 4 weeks
DIETARY_SUPPLEMENT	Placebo	300 mg, once daily of placebo for 4 weeks

Timeline

• Start date: 2024-08-19
• Primary completion: 2025-03-01
• Completion: 2025-03-01
• First posted: 2024-07-15
• Last updated: 2025-04-13

Locations

1 site across 1 country: United States