NCT06501170

Risk Stratification for Abdominal Emergency Surgery: a Cohort Study

Risk Factors of Adverse Outcomes After Emergency Abdominal Emergency Surgery and Establishment of a Risk Stratification Tool

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 1,000 (estimated)
• Sponsor: Peking Union Medical College Hospital · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

The goal of this retrospective observational study is to identify risk factors of unwanted outcomes (in-hospital morbidity and mortality) among patients undergoing emergency abdominal surgery.

Detailed description

Patients undergoing emergency abdominal surgery at a single tertiary care institution with a high volume of emergency abdominal surgeries, especially for high-acuity patients, between January 1, 2023, and June 1, 2024, will be included. Baseline demographics, indication for surgery, and preoperative status (respiratory support, cardiovascular stability, Glasgow score, SOFA score, preoperative lab results, and preoperative waiting time including Time to Theatre (TTT) and Time to Knife (TTK)) will be recorded. Definitions: Time to Theatre (TTT): The duration from when it is determined that the patient needs surgery to the time the patient arrives at the operating theatre. Time to Knife (TTK): The duration from when the patient enters the operating theatre to the time the first incision is made. These data will be retrieved from the electronic health record system. Intraoperative factors, including ASA classification, anesthesia method, type of surgical intervention, intraoperative lab results, transfusions, input/output (I/O), inotropic/vasopressor usage, and discharge ward, will also be retrieved from the electronic health record system. Postoperative outcomes, including in-hospital mortality and morbidity (complications stratified by the Clavien-Dindo classification system), will be assessed by trained investigators. Secondary outcomes include postoperative length of hospital stay and health care costs. A statistical model will be built to identify risk factors for morbidity and mortality.

Conditions

• Emergency Surgery

Interventions

Type	Name	Description
OTHER	Retrospective Data Analysis of Emergency Abdominal Surgery Outcomes	Retrospective Data Analysis of Emergency Abdominal Surgery Outcomes

Timeline

• Start date: 2024-06-01
• Primary completion: 2025-02-27
• Completion: 2025-06-01
• First posted: 2024-07-15
• Last updated: 2025-03-07

Locations

1 site across 1 country: China