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RecruitingNCT06499779

Prescription of Valproate and Derivatives in Women of Childbearing Age: Qualitative Study

Status
Recruiting
Phase
Study type
Observational
Enrollment
50 (estimated)
Sponsor
University Hospital, Strasbourg, France · Academic / Other
Sex
Female
Age
16 Years
Healthy volunteers
Not accepted

Summary

The prescription of valproate in women of childbearing age has decreased by 82% in France, for mood disorders. Exposure to valproate during pregnancy 60%. However, the ANSM sent an alert document in August 2022 because there are still patients on valproate. In addition, there were 32 births taking valproate to mothers with bipolar disorder in 2018. The risks of exposure during pregnancy which occur in 10% of exposure cases are: congenital malformations; neurodevelopmental disorders including autism spectrum disorders, attention deficit disorders more or less hyperactivity, language disorders, motor disorders, mental delays; reduction in social, attentional, motor and language abilities; a lower level of education.

Conditions

Timeline

Start date
2024-01-02
Primary completion
2026-05-01
Completion
2026-05-02
First posted
2024-07-12
Last updated
2024-07-12

Locations

1 site across 1 country: France

Source: ClinicalTrials.gov record NCT06499779. Inclusion in this directory is not an endorsement.