NCT06499480

Italian Registry of Allergen ImmunoTherapy

Italian Registry of Patients With Allergic Disease and Treated With Allergen ImmunoTherapy

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 5,000 (estimated)
• Sponsor: Società Italiana di Allergologia, Asma e Immunologia Clinica · Academic / Other
• Sex: All
• Age: 1 Year
• Healthy volunteers: Not accepted

Summary

RIAIT (Italian Registry of Allergy Immunotherapy) is a multicenter observational study that aims to prospectively collect the most extensive data available on Italian patients using AIT for respiratory allergies (rhinoconjunctivitis and/or asthma) in a real-life context, through a network of allergy centers with specific interest and expertise in the management of allergic respiratory patients.

Detailed description

Objectives include: * Evaluate short and long-term real-life effectiveness and safety of AIT overall, in specific patient groups' phenotypes and with specific AIT products. * Evaluate the pertinence and differences in suggesting AIT to a patient comparing physician's evaluation in various settings with established international guidelines, describing the factors associated with treatment choices and changing over time, and promoting interoperability, data sharing, and cross-comparison among centers. * Describe long-term respiratory allergic disease evolution in patients treated with AIT. * Describe the natural history of the patient population with respiratory allergies and identify patient groups describing their illness burden, management patterns, and clinical progression. * Promote the creation of accurate, standardized, and efficient processes for diagnosing and treating respiratory allergic diseases, especially with AIT. * Assess biomarker data to predict diagnosis, treatment response and long-term disease progression.

Conditions

• Allergic Respiratory Disease

Timeline

• Start date: 2024-05-01
• Primary completion: 2035-12-31
• Completion: 2035-12-31
• First posted: 2024-07-12
• Last updated: 2025-03-06

Locations

2 sites across 1 country: Italy