NCT06498700

Intraoperative Subanesthetic Ketamine Versus Dexmedetomidine Infusion for Prevention of Post-traumatic Stress Disorder After Traumatic Brain Surgeries

Intraoperative Subanesthetic Ketamine Versus Dexmedetomidine Infusion for Prevention of Post-traumatic Stress Disorder After Traumatic Brain Surgeries: A Randomized Trial

• Status: Enrolling By Invitation
• Phase: N/A
• Study type: Interventional
• Enrollment: 52 (estimated)
• Sponsor: Zagazig University · Other Government
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

Prevention of Post-traumatic Stress Disorder after traumatic Brain surgeries by using either subanesthetic ketamine or dexmedetomidine infusion.

Detailed description

after being informed about the study and potential risks. All patients giving written consent will be randomized by double blind manner into two equal groups (K group and D group). Using computer generated randomization table; each group consists of 26 patients: K group (n=26): Patient will receive with 0.5 mg/kg/h ketamine infusion. D group (n=26): Patient will receive 0.1 ug/kg/h dexmedetomidine infusion.

Conditions

• Subanesthetic Ketamine Dexmedetomidin

Interventions

Type	Name	Description
DRUG	ketamine	0.5 mg/kg/h ketamine infusion
DRUG	dexmedetomidine	0.1 ug/kg/h dexmedetomidine infusion

Timeline

• Start date: 2024-07-15
• Primary completion: 2024-12-15
• Completion: 2025-03-15
• First posted: 2024-07-12
• Last updated: 2024-08-19

Locations

1 site across 1 country: Egypt