NCT06497647

New Treatment for Nocturnal Enuresis in Children

Outcome of Treatment of Monosymptomatic Nocturnal Enuresis in Children Using Imipramine Alone Versus Sulbutiamine Alone Versus Imipramine Plus Sulbutiamine : Prospective Comparative Study

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 450 (estimated)
• Sponsor: Sohag University · Academic / Other
• Sex: All
• Age: 6 Years – 18 Years
• Healthy volunteers: Accepted

Summary

The aim of the study is to evaluate the role of sulbutiamine in treatment of monosymptomatic nocturnal enuresis in children by using it alone or as a combination therapy with tricyclic antidepressants (imipramine+sulbutiamine).

Conditions

• Nocturnal Enuresis in Children

Interventions

Type	Name	Description
DRUG	Sulbutiamine	sulbutiamine will be used by oral route 100 mg daily for 1 month and follow up will be done every 1 month till 3 months. it will be used alone in group B and combined with imipramine in group C
DRUG	Imipramine	imipramine will be used by oral route 25 mg daily for 1 month and follow up will be done every 1 month till 3 months. it will be used alone in group A and combined with sulbutiamine in group C

Timeline

• Start date: 2024-03-01
• Primary completion: 2024-09-01
• Completion: 2024-11-01
• First posted: 2024-07-12
• Last updated: 2024-07-12

Locations

1 site across 1 country: Egypt