NCT06495385

Evaluation of a Multidisciplinary Care Pathway on the Evolution of Renal Function in Patients With Advanced Chronic Kidney Disease

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 535 (estimated)
• Sponsor: Centre Hospitalier Universitaire de Saint Etienne · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The number of incident and prevalent patients with end stage renal disease on dialysis treatment is increasing in France and worldwide. A quarter of dialysis patients are initiating dialysis urgently through central venous catheters and the number of patients registered in the waiting list for renal transplantation before dialysis initiation is very low. This is also reflected in the very low number of pre-emptive renal transplantations. In order to reduce the number of dialysis patients, the French state has induced a national program proposing a multidisciplinary care pathway including the nephrology visits and at least one consultation with a dietitian and a specialist renal nurse in all patients with Chronic Kidney Disease stage 4 and 5.

Detailed description

The aim of this single-center retrospective study is to evaluate the influence of the complete, partial or no participation in this program on the evolution of renal function and clinicobiological parameters in this group of patients.

Conditions

• Chronic Kidney Disease stage4
• Chronic Kidney Disease Stage 5

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Evolution of renal function	Plasma creatinine levels and glomerular filtration rate estimated using the CKD-Epi formula adjusted for 1.73 m2 body surface area will be measured.
DIAGNOSTIC_TEST	Measurement of haemoglobin levels	Haemoglobin levels will be measured.
DIAGNOSTIC_TEST	Measurement of biological parameters	Plasma levels of urea, calcium, phosphorus and parathyroid hormone, as well as alkaline reserve, will be measured.
DIAGNOSTIC_TEST	Measure sodium and protein consumption	24-hour urine volume, proteinuria, urea and sodium, will be measured.
BEHAVIORAL	Quality of life questionnaire EUROQOL 5 dimensions (EQ-5D-5L)	The descriptive system comprises five dimensions: mobility, personal care, usual activities, pain/discomfort and anxiety/depression. Each dimension has 5 levels: no problems, mild problems, moderate problems, severe problems and extreme problems. The figures for the five dimensions can be combined into a 5-digit number describing the patient's state of health. Scores close to 1 indicate "the best health you can imagine" and those close to 0 "the worst health you can imagine".

Timeline

• Start date: 2024-04-09
• Primary completion: 2024-05-22
• Completion: 2024-09-01
• First posted: 2024-07-10
• Last updated: 2024-07-10

Locations

1 site across 1 country: France