Trials / Recruiting
RecruitingNCT06489444
Fecal Amino Acids，Gut Taste Receptors and Irritable Bowel Syndromes
Alterations in Nutrient-sensing Mechanisms May Play a Role in Symptom Generation in Patients With IBS
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 100 (estimated)
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University · Academic / Other
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Accepted
Summary
Clinical data, fresh feces and intestinal mucosal tissues of patients with diarrheal IBS were collected. High performance liquid chromatography, immunohistochemistry and immunofluorescence were used to study the amino acid levels in feces of patients with IBS, the expression of taste receptors in intestinal mucosa, and the correlation between symptoms of abdominal pain and diarrhea and the expression of taste receptors, so as to obtain the conclusion that "intestinal amino acid perception abnormalities exist in patients with IBS. And correlated with clinical symptoms."
Conditions
Timeline
- Start date
- 2023-03-16
- Primary completion
- 2024-08-01
- Completion
- 2024-08-01
- First posted
- 2024-07-08
- Last updated
- 2024-07-08
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT06489444. Inclusion in this directory is not an endorsement.