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RecruitingNCT06489119

Single-cell Multi-omics Analyses of OCT-diagnosed Plaque Subtypes in Coronary Artery Disease (MOOP-CAD)

Single-cell Multi-omics Analyses of OCT-diagnosed Plaque Subtypes in Coronary Artery Disease - a Prospective, Observational Study

Status
Recruiting
Phase
Study type
Observational
Enrollment
350 (estimated)
Sponsor
Harbin Medical University · Academic / Other
Sex
All
Age
18 Years – 85 Years
Healthy volunteers
Accepted

Summary

The MOOP-CAD study program characterizes, for the first time, the pathophysiological processes and molecular mechanisms of coronary atherosclerotic plaque progression by combining in vivo intravascular imaging techniques with circulating immune single-cell multi-omics analysis. In this study, the investigators evaluate the imaging characteristics of coronary plaques by optical coherence tomography (OCT) and invasive angiography, and study the correlation between plaque characteristics and the multi-omics immune characteristic profiles.

Conditions

Timeline

Start date
2024-07-07
Primary completion
2026-01-15
Completion
2026-07-15
First posted
2024-07-05
Last updated
2025-09-15

Locations

2 sites across 1 country: China

Source: ClinicalTrials.gov record NCT06489119. Inclusion in this directory is not an endorsement.

Single-cell Multi-omics Analyses of OCT-diagnosed Plaque Subtypes in Coronary Artery Disease (MOOP-CAD) (NCT06489119) · Clinical Trials Directory