NCT06488417

Frankincense Supplements and Inflammation

Evaluation of Frankincense Essential Oil Supplements on Markers of Inflammation and Cellular Health

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 67 (actual)
• Sponsor: dōTERRA International · Industry
• Sex: All
• Age: 18 Years – 64 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to learn whether frankincense essential oil-based supplements can affect gene expression and serum protein markers in healthy volunteers. The main questions it aims to answer are: 1. Do frankincense essential oil supplements affect gene expression and protein markers as measured in blood? 2. How does daily ingestion of frankincense supplements affect anthropometric measurements, including body mass index, waist circumference, blood pressure, and heart rate? 3. How does daily ingestion of frankincense essential oil supplements affect subjective quality of life and health parameters? 4. Is ingesting frankincense essential oil supplements daily safe, as measured by laboratory tests and adverse events? Researchers will compare two types of frankincense essential oil supplements. One type contains frankincense essential oil and boswellic acid as its active ingredients. The other type contains only frankincense essential oil as its active ingredient. Participants will: * Be assigned one of the two types of frankincense essential oil supplement * Take two capsules of their assigned supplement every day for about 30 days * Attend two study visits in which they provide blood and urine samples, complete subjective health and quality of life assessments, and undergo anthropometric measurements * Complete weekly subjective health assessments from home

Detailed description

This randomized, double-blind study will recruit healthy men and women to compare gene expression profile and serum protein markers before and after consumption of frankincense essential oil supplements for approximately 4 weeks. Quality of life will also be assessed using subjective surveys and questionnaires. Safety markers (liver and kidney function, hematology, urinalysis, and adverse events) will be collected.

Conditions

• Healthy

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Frankincense essential oil + boswellic acid supplement	This supplement contains frankincense essential oil and boswellic acid as its active ingredients.
DIETARY_SUPPLEMENT	Frankincense essential oil supplement	This supplement contains frankincense essential oil as its active ingredient.

Timeline

• Start date: 2024-06-17
• Primary completion: 2024-08-12
• Completion: 2024-08-21
• First posted: 2024-07-05
• Last updated: 2024-08-22

Locations

1 site across 1 country: United States