NCT06482489

Accurate Prostate Cancer Following Using Low-Field MRI (Low-PRISM)

Comparing Prostate Cancer Screening Between Standardized 3T MRI Screening Protocol and Low-Field MRI in a Prospective Study

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 74 (estimated)
• Sponsor: University of Lausanne Hospitals · Academic / Other
• Sex: Male
• Age: 18 Years
• Healthy volunteers: —

Summary

This study compares the effectiveness of low-field MRI (0.55T) with high-field MRI (3T) in prostate cancer screening and image quality. It consists of three phases: optimizing the low-field MRI protocol with healthy volunteers, evaluating image quality in patients with metallic artifacts (like hip prostheses), and assessing low-field MRI in patients with suspicious prostate lesions found on high-field MRI.

Detailed description

This study aims to compare the effectiveness of low-field MRI (0.55T) with traditional high-field MRI (3T) in prostate cancer screening and image quality improvement. The study is conducted in three phases: first, a pilot study with healthy volunteers to optimize the low-field MRI protocol; second, an evaluation of image quality between the two types of MRI in patients with metallic artifacts, particularly due to hip prostheses; and finally, the assessment of low-field MRI in patients with suspicious prostate lesions on high-field MRI (3T). The goal is to find an accessible solution for prostate cancer screening while maintaining or improving image quality.

Conditions

• Prostate Cancer

Interventions

Type	Name	Description
DEVICE	Siemens Magnetom Free.Max 0.55T (Siemens Healthineers, Erlangen, Germany).	Performing low-field MRI to evaluate image quality with patients carrying metallic implants and assess the detection of suspicious prostate lesions.

Timeline

• Start date: 2024-11-01
• Primary completion: 2025-05-31
• Completion: 2025-07-31
• First posted: 2024-07-01
• Last updated: 2025-04-03

Locations

1 site across 1 country: Switzerland