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Trials / Completed

CompletedNCT06482437

Safety and Efficacy of NMD670 in Adult Patients With Type 1 and Type 2 Charcot-Marie-Tooth Disease

A Phase 2a, Randomised, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Tolerability of NMD670 Over 21 Days in Ambulatory Adult Patients With Type 1 and Type 2 Charcot-Marie-Tooth Disease

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
81 (actual)
Sponsor
NMD Pharma A/S · Industry
Sex
All
Age
18 Years – 70 Years
Healthy volunteers
Not accepted

Summary

This Phase 2a study aims to evaluate the efficacy, safety and tolerability of NMD670 vs placebo administered twice a day (BID) for 21 days in ambulatory adult patients with Charcot-Marie-Tooth disease type 1 and type 2.

Conditions

Interventions

TypeNameDescription
DRUGNMD670Tablets taken twice daily for 21 days
DRUGPlaceboTablets taken twice daily for 21 days

Timeline

Start date
2024-09-30
Primary completion
2025-10-28
Completion
2025-11-04
First posted
2024-07-01
Last updated
2025-11-12

Locations

19 sites across 5 countries: United States, Belgium, Denmark, France, Spain

Regulatory

Source: ClinicalTrials.gov record NCT06482437. Inclusion in this directory is not an endorsement.

Safety and Efficacy of NMD670 in Adult Patients With Type 1 and Type 2 Charcot-Marie-Tooth Disease (NCT06482437) · Clinical Trials Directory