NCT06480279

Assessing Fall Risk Using Transcranial Magnetic Stimulation and Quantitative Sensory Testing

Development of Artificial Intelligence Innovation for Assessing Fall Risk Using Clinical Neurological Studies With Transcranial Magnetic Stimulation and Quantitative Sensory Testing in the Thai Elderly

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 150 (actual)
• Sponsor: Chulalongkorn University · Academic / Other
• Sex: All
• Age: 65 Years – 80 Years
• Healthy volunteers: —

Summary

The elderly are at high risk of falls due to neurophysiological changes, such as motor and sensory impairment, that occur with aging. The incidence of falls in older adults is high, with approximately 30% of adults over the age of 65 falling at least once per year. Falls can lead to serious consequences such as fractures, hospitalization, and loss of independence. The changes in neurophysiology have also been found to decrease balance control in aging people, leading to postural instability. It is well-known that postural balance is influenced by sensory inputs, including touch, proprioception, vision, and vestibular, as well as motor output such as motor controls. Impairments in these systems contribute to postural instability and an increased risk of falling in the elderly.

Detailed description

The data collection will be arranged in the same order. Practice trials will be provided before the start of the data collection. The entire data collection session will take approximately 90 minutes. Data collection will be conducted for both the baseline and the 3-month follow-up. The data collection will include: 1. Demographic information such as age, sex, body height, body weight, body mass index, medical history, medical diagnosis, body composition, and the MoCA (Montreal Cognitive Assessment). 2. Neurophysiological assessments such as electromyography and Quantitative Sensory Testing (QST). 3. Functional tests such as the Timed up and go test and Chait stand test.

Conditions

• Fall

Timeline

• Start date: 2024-05-16
• Primary completion: 2025-05-16
• Completion: 2025-08-16
• First posted: 2024-06-28
• Last updated: 2025-09-25

Locations

1 site across 1 country: Thailand