NCT06479122

Efficacy of Acetaminophen Alone Versus Combination of Acetaminophen/Ibuprofen After Cesarean Section

Efficacy of Intravenous Acetaminophen Alone Versus Combination of Acetaminophen/Ibuprofen (Maxigesic®IV) in Multimodal Analgesia After Cesarean Section: a Randomized Controlled Trial

• Status: Recruiting
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 84 (estimated)
• Sponsor: Seoul National University Hospital · Academic / Other
• Sex: Female
• Age: 19 Years
• Healthy volunteers: Accepted

Summary

The investigators aim to compare the analgesic efficacy of intravenous acetaminophen alone versus combination of acetaminophen/ibuprofen (Maxigesic®IV) in multimodal analgesia after cesarean section.

Conditions

• Cesarean Section
• Postoperative Pain

Interventions

Type	Name	Description
DRUG	Acetaminophen	1g acetaminophen is administered during skin closure (end of operation).
DRUG	Acetaminophen/Ibuprofen	A mixture of 1g acetaminophen and 300 mg ibuprofen (Maxigesic®IV) is administered during skin closure (end of operation)
DRUG	Acetaminophen	1g acetaminophen is administered 6 hours after the first administration.
DRUG	Acetaminophen/Ibuprofen	A mixture of 1g acetaminophen and 300 mg ibuprofen (Maxigesic®IV) is administered 6 hours after the first administration.

Timeline

• Start date: 2024-10-09
• Primary completion: 2026-06-25
• Completion: 2026-08-25
• First posted: 2024-06-28
• Last updated: 2025-06-04

Locations

1 site across 1 country: South Korea