NCT06477107

A Study of Cerebral Perfusion With tDCS in Chronic Hypoperfusion

Augmenting Cerebral Perfusion With Transcranial Direct Current Stimulation (tDCS) in Chronic Hypoperfusion States

• Status: Enrolling By Invitation
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Mayo Clinic · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study is being done to examine whether transcranial direct current stimulation (tDCS) will increase cerebral blood flow which may provide a clinical benefit such as improving cognitive impairment.

Conditions

• Moyamoya Syndrome
• Moyamoya Disease
• Atheroscleroses, Cerebral

Interventions

Type	Name	Description
DEVICE	Soterix® 4x1HD-TDCS	Is intended for inducing cortical neuromodulation for research and treatment purposes.
DEVICE	Soterix® 1x1 tDCS	At-home remotely supervised transcranial direct current stimulation (tDCS) at an intensity of 2 mA for 20 minutes per session, with slow ramp-up and automatic turn off once it reaches the maximal intensity.
BEHAVIORAL	Cognitive training program	Computerized cognitive therapy for 45 minutes per day that starts at the same time with stimulation

Timeline

• Start date: 2024-10-24
• Primary completion: 2026-06-01
• Completion: 2026-06-01
• First posted: 2024-06-27
• Last updated: 2026-01-20

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study