Trials / Recruiting
RecruitingNCT06477029
Examination of Transcranial Focused Ultrasound on Brain Activity in Adults
Modulating Ventral Striatal Activity and Connectivity With Transcranial Focused Ultrasound as a Putative Novel Intervention for Cocaine Use Disorder
- Status
- Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 31 (estimated)
- Sponsor
- Mary Phillips, MD MD (Cantab) · Academic / Other
- Sex
- All
- Age
- 18 Years – 45 Years
- Healthy volunteers
- Accepted
Summary
The investigators aim to examine the immediate effect of transcranial focused ultrasound (tFUS) on brain activity in healthy adults.
Detailed description
The investigators will examine ventral striatum (VS) target engagement by tFUS in healthy adults using a reward processing task that reliably activates the VS.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | tFUS | tFUS is a brief stimulation of a part of the brain called the ventral striatum with low-intensity sound waves that pass through the scalp and skull safely. |
| DEVICE | Sham tFUS | Sham tFUS goes through the motions of applying tFUS to the brain. Participants will know that one session will be a sham, but they will be blinded to which session is the sham |
Timeline
- Start date
- 2024-10-10
- Primary completion
- 2026-04-13
- Completion
- 2026-04-13
- First posted
- 2024-06-27
- Last updated
- 2026-04-07
Locations
1 site across 1 country: United States
Regulatory
- FDA-regulated device study
Source: ClinicalTrials.gov record NCT06477029. Inclusion in this directory is not an endorsement.