NCT06472232

Multicenter Study of Chloroprocaine Versus Ropivacaine for Epidural Labor Analgesia

Efficacy and Safety of Chloroprocaine Versus Ropivacaine for Epidural Labor Analgesia Study: a Randomized, Double-blind, Controlled, Multicenter, Noninferiority Clinical Trial

• Status: Not Yet Recruiting
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 356 (estimated)
• Sponsor: Women's Hospital School Of Medicine Zhejiang University · Academic / Other
• Sex: Female
• Age: 20 Years
• Healthy volunteers: Not accepted

Summary

Women requiring epidural labor analgesia were randomized into two groups, one with the local anesthetic chloroprocaine and the other with ropivacaine. The primary outcome was to observe the analgesic scores of the two groups of drugs as well as adverse reactions.

Detailed description

Mothers who met the study criteria vertebrae were included and then divided into two groups. Labor analgesia was provided by epidural anesthesia with a low concentration of local anesthetic (chloroprocaine or ropivacaine) combined with sufentanil. Data related to labor analgesia such as pain scores, motor tissue scores, and body temperature were collected and statistically analyzed to compare the efficacy and adverse effects of the two local anesthetics and to draw conclusions.

Conditions

• Obstetric Labor

Interventions

Type	Name	Description
DRUG	Chloroprocaine	Selection of low concentration of chloroprocaine as local anesthetic for labor analgesia

Timeline

• Start date: 2024-06-18
• Primary completion: 2025-06-16
• Completion: 2025-09-30
• First posted: 2024-06-25
• Last updated: 2024-06-25