NCT06470477

Molecular Characteristics of Phlegm-heat Syndrome in Ischemic Stroke

Molecular Characteristics of Phlegm-heat Syndrome in Ischemic Stroke: A Cohort Study

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 84 (estimated)
• Sponsor: Dongzhimen Hospital, Beijing · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The molecular characteristics of ischemic stroke with phlegm-heat syndrome and candidate biomarkers were identified based on multi-omics data. The main purpose of this study is to validate the molecular characteristics and biomarkers of phlegm-heat syndrome in ischemic stroke, and to demonstrate the association of biomarkers with clinical outcomes.

Detailed description

This is a cohort study in patients with acute ischemic stroke. The demographic characteristics, Traditional Chinese Medicine (TCM) syndromes, and other baseline information will be recorded. At the same time, baseline peripheral blood will be collected. These participants will be followed up to 90 days of onset, and 90-day modified Rankin scale (mRS) scores will be assessed. The collected blood samples will be tested by multi-factor detection technology for candidate biomarkers.

Conditions

• Ischemic Stroke, Acute

Interventions

Type	Name	Description
DRUG	Guideline-based treatment	Guideline-based treatment includes anti-platelet therapy, control of vascular risk factors, and so on.

Timeline

• Start date: 2024-06-20
• Primary completion: 2024-12-31
• Completion: 2024-12-31
• First posted: 2024-06-24
• Last updated: 2024-06-24

Locations

1 site across 1 country: China