NCT06469788

Testimonials and Navigation in Rheumatology

Improving COVID-19 Vaccine Uptake Among Racial and Ethnic Minority Groups With Rheumatic Diseases

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 1,170 (estimated)
• Sponsor: University of Alabama at Birmingham · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The overall goal of this study is to determine whether a novel, multi-modal, patient-directed behavioral intervention initiated in rheumatology clinics is an effective approach to improve uptake of updated COVID-19 vaccine.

Detailed description

Black and Latinx persons are at higher risk for certain autoimmune and inflammatory rheumatic diseases (AIRD) and have experienced worse COVID-19 outcomes compared to their white counterparts. Given the risks of severe COVID-19 outcomes such as hospitalization and death in people with AIRD, COVID-19 vaccine is recommended in this population. Historically, overall vaccine uptake among people with AIRDs has been low, and this vaccine reluctance has extended to COVID-19 vaccination. While additional COVID-19 vaccine doses have offered considerable added protection against severe outcomes, only 20% of all vaccinated persons in Alabama (AL) and 45% in Massachusetts have obtained an additional dose of COVID-19 vaccine as of October 2022. Racial and ethnic minority groups have faced disparities in obtaining subsequent COVID-19 vaccines, particularly in under-resourced communities, including those in Alabama and Massachusetts. Together, these obstacles exacerbate existing health inequities among people of color and perpetuate worse COVID-19 outcomes. We will conduct a randomized controlled study to test an intervention that seeks to address gaps in COVID-19 vaccine information and access inequities common in Black and Latinx populations.

Conditions

• Rheumatologic Disease
• Autoimmune Diseases

Interventions

Type	Name	Description
BEHAVIORAL	Video comprised of AIRD patient narratives on COVID-19 vaccination thoughts and experiences	Participants will watch video focused on the importance of receipt of updated COVID-19 vaccination in patients with AIRD
BEHAVIORAL	Video on the importance of good oral health for patients with AIRD	Participants will watch video on the importance of good oral health in AIRD patients.
BEHAVIORAL	Brochure on COVID-19 vaccination in AIRD patients	Participants
BEHAVIORAL	Patient Navigation	Participants will receive phone calls from patient navigators to provide support and information for receipt of updated COVID-19 vaccination in patients with AIRD
BEHAVIORAL	Brochure on the importance of good oral health in AIRD patients	Participants will receive a brochure on the importance of good oral health in AIRD patients.

Timeline

• Start date: 2024-12-18
• Primary completion: 2027-06-30
• Completion: 2028-02-28
• First posted: 2024-06-24
• Last updated: 2026-04-17

Locations

3 sites across 1 country: United States