NCT06469216

Efficacy of Hyaluronic Acid in Prevention of Acute Radiation Proctitis

Efficacy of Hyaluronic Acid in Prevention of Acute Radiation Proctitis: Multi-center, Double-blind, Randomized Controlled Trial

• Status: Completed
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 44 (actual)
• Sponsor: Assiut University · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

A randomized placebo-controlled clinical trial to evaluate efficacy of hyaluronic acid in prevention of acute radiation proctitis among oncology patient population especially who are diagnosed with abdomeno-pelvic tumors and subsequently required radiotherapy.

Conditions

• Acute Radiation Proctitis
• Acute Radiation Enteritis

Interventions

Type	Name	Description
DRUG	Hyaluronic Acid	Hyaluronic Acid to be used as sodium hyaluronate powder plus inactive ingredient (Carboxy methyl cellulose) and to be dissolved in distilled water
OTHER	Placebo	Inactive ingredient (Carboxy methyl cellulose) to be used as powder and to be dissolved in distilled water

Timeline

• Start date: 2024-04-01
• Primary completion: 2024-12-01
• Completion: 2024-12-01
• First posted: 2024-06-21
• Last updated: 2025-01-22

Locations

2 sites across 1 country: Egypt