NCT06467409

Phase II Clinical Trial to Evaluate the Efficacy and Safety of LPM3480392 Injection for Moderate to Severe Pain After Orthopedic Surgery

A Multicenter, Randomized, Double-blind, Placebo, Positive Drug Parallel Controlled Phase II Clinical Trial to Evaluate the Efficacy and Safety of LPM3480392 Injection for Moderate to Severe Pain After Orthopedic Surgery

• Status: Recruiting
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 150 (estimated)
• Sponsor: Luye Pharma Group Ltd. · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

A randomized, double-blind, placebo/positive drug parallel controlled design was used to evaluate the preliminary efficacy and safety of intravenous infusion of LPM3480392 injection using different dosing regimens in subjects with moderate to severe pain after Orthopedic surgery

Conditions

• Pain, Postoperative

Interventions

Type	Name	Description
DRUG	Placebo	patient-controlled analgesia(PCA) administration
DRUG	morphine hydrochloride injection	patient-controlled analgesia(PCA) administration
DRUG	LPM3480392 Injection	patient-controlled analgesia(PCA) administration
DRUG	LPM3480392 Injection	patient-controlled analgesia(PCA) administration
DRUG	LPM3480392 Injection	patient-controlled analgesia(PCA) administration
DRUG	LPM3480392 Injection	patient-controlled analgesia(PCA) administration

Timeline

• Start date: 2024-01-26
• Primary completion: 2025-01-01
• Completion: 2025-01-01
• First posted: 2024-06-21
• Last updated: 2024-06-21

Locations

1 site across 1 country: China