Clinical Trials Directory

Trials / Completed

CompletedNCT06466473

A Study to Learn How Different Forms of The Study Medicine Called Phenytoin Are Taken up Into the Blood in Healthy Adults

A PHASE 1, OPEN-LABEL, RANDOMIZED, SINGLE-DOSE, 2-WAY CROSSOVER, PIVOTAL BIOEQUIVALENCE STUDY COMPARING 50-MG CHEWABLE DILANTIN® INFATABS® MANUFACTURED AT VEGA BAJA (PUERTO RICO) AND ASCOLI (ITALY) IN HEALTHY ADULT PARTICIPANTS UNDER FASTING CONDITIONS

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
35 (actual)
Sponsor
Pfizer · Industry
Sex
All
Age
18 Years
Healthy volunteers
Accepted

Summary

The purpose of this study is to understand how the different formulation of phenytoin is taken up into the blood in Healthy Adults. This study is seeking healthy adult participants. All the study participants will receive Phenytoin 50 mg chewable tablets manufactured at Ascoli and Vega Baja manufacturing site. We will measure how the phenytoin will be taken up into the blood in Healthy Adults following oral dosing of Phenytoin. This will help us determine if the Phenytoin 50 mg chewable tablets manufactured at Ascoli and Vega Baja manufacturing site are similar or not.

Conditions

Interventions

TypeNameDescription
DRUGPhenytoin (Ascoli)Phenytoin 50mg chewable tablets
DRUGPhenytoin (Vega Baja)Phenytoin 50mg chewable tablets

Timeline

Start date
2024-07-03
Primary completion
2024-10-04
Completion
2024-10-04
First posted
2024-06-20
Last updated
2024-10-08

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT06466473. Inclusion in this directory is not an endorsement.